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Do Zebrafish Obey Lipinski Rules?

[Image: see text] The use of zebrafish in whole organism phenotypic assays has become a valuable strategy throughout the drug discovery process. Zebrafish assays can be used not only to screen libraries of compounds at the earliest stages but also to evaluate advanced leads for their effects on spec...

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發表在:ACS Med Chem Lett
Main Authors: Long, Keith, Kostman, Stephen J., Fernandez, Christian, Burnett, James C., Huryn, Donna M.
格式: Artigo
語言:Inglês
出版: American Chemical Society 2019
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580538/
https://ncbi.nlm.nih.gov/pubmed/31223462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00063
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