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Do Zebrafish Obey Lipinski Rules?

[Image: see text] The use of zebrafish in whole organism phenotypic assays has become a valuable strategy throughout the drug discovery process. Zebrafish assays can be used not only to screen libraries of compounds at the earliest stages but also to evaluate advanced leads for their effects on spec...

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Библиографические подробности
Опубликовано в: :ACS Med Chem Lett
Главные авторы: Long, Keith, Kostman, Stephen J., Fernandez, Christian, Burnett, James C., Huryn, Donna M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2019
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580538/
https://ncbi.nlm.nih.gov/pubmed/31223462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00063
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