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Do Zebrafish Obey Lipinski Rules?

[Image: see text] The use of zebrafish in whole organism phenotypic assays has become a valuable strategy throughout the drug discovery process. Zebrafish assays can be used not only to screen libraries of compounds at the earliest stages but also to evaluate advanced leads for their effects on spec...

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Publicado en:ACS Med Chem Lett
Autores principales: Long, Keith, Kostman, Stephen J., Fernandez, Christian, Burnett, James C., Huryn, Donna M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2019
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580538/
https://ncbi.nlm.nih.gov/pubmed/31223462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00063
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