Zebrafish model of amyloid light chain cardiotoxicity: regeneration versus degeneration

Cardiac dysfunction is the most frequent cause of morbidity and mortality in amyloid light chain (AL) amyloidosis caused by a clonal immunoglobulin light chain (LC). Previously published transgenic animal models of AL amyloidosis have not recapitulated the key phenotype of cardiac dysfunction seen i...

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Détails bibliographiques
Publié dans:Am J Physiol Heart Circ Physiol
Auteurs principaux: Mishra, Shikha, Joshi, Shaurya, Ward, Jennifer E., Buys, Eva P., Mishra, Deepak, Mishra, Deepa, Morgado, Isabel, Fisch, Sudeshna, Lavatelli, Francesca, Merlini, Giampaolo, Dorbala, Sharmila, MacRae, Calum A., Liao, Ronglih
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580397/
https://ncbi.nlm.nih.gov/pubmed/30875258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00788.2018
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