Bacillus anthracis lethal toxin, but not edema toxin, increases pulmonary artery pressure and permeability in isolated perfused rat lungs

Although lethal toxin (LT) and edema toxin (ET) contribute to lethality during Bacillus anthracis infection, whether they increase vascular permeability and the extravascular fluid accumulation characterizing this infection is unclear. We employed an isolated perfused Sprague-Dawley rat lung model t...

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Gepubliceerd in:Am J Physiol Heart Circ Physiol
Hoofdauteurs: Cui, Xizhong, Xu, Wanying, Neupane, Pranita, Weiser-Schlesinger, Andie, Weng, Ray, Pockros, Benjamin, Li, Yan, Moayeri, Mahtab, Leppla, Stephen H., Fitz, Yvonne, Eichacker, Peter Q.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2019
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580392/
https://ncbi.nlm.nih.gov/pubmed/30767685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00685.2018
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