Shock and lethality with anthrax edema toxin in rats are associated with reduced arterial responsiveness to phenylephrine and are reversed with adefovir

Although edema toxin (ETx) and lethal toxin (LTx) contribute to Bacillus anthracis shock and lethality, the mechanisms underlying their cardiovascular effects are unclear. We have previously shown that ETx but not LTx inhibited phenylephrine-stimulated contraction of aortic rings prepared from healt...

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Bibliografiska uppgifter
I publikationen:Am J Physiol Heart Circ Physiol
Huvudupphovsmän: Suffredini, Dante A., Li, Yan, Xu, Wanying, Moayeri, Mahtab, Leppla, Stephen, Fitz, Yvonne, Cui, Xizhong, Eichacker, Peter Q.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792197/
https://ncbi.nlm.nih.gov/pubmed/28887331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00285.2017
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