Bacillus anthracis lethal toxin, but not edema toxin, increases pulmonary artery pressure and permeability in isolated perfused rat lungs

Although lethal toxin (LT) and edema toxin (ET) contribute to lethality during Bacillus anthracis infection, whether they increase vascular permeability and the extravascular fluid accumulation characterizing this infection is unclear. We employed an isolated perfused Sprague-Dawley rat lung model t...

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Vydáno v:Am J Physiol Heart Circ Physiol
Hlavní autoři: Cui, Xizhong, Xu, Wanying, Neupane, Pranita, Weiser-Schlesinger, Andie, Weng, Ray, Pockros, Benjamin, Li, Yan, Moayeri, Mahtab, Leppla, Stephen H., Fitz, Yvonne, Eichacker, Peter Q.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580392/
https://ncbi.nlm.nih.gov/pubmed/30767685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00685.2018
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