Bacillus anthracis lethal toxin, but not edema toxin, increases pulmonary artery pressure and permeability in isolated perfused rat lungs

Although lethal toxin (LT) and edema toxin (ET) contribute to lethality during Bacillus anthracis infection, whether they increase vascular permeability and the extravascular fluid accumulation characterizing this infection is unclear. We employed an isolated perfused Sprague-Dawley rat lung model t...

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Bibliographic Details
Published in:Am J Physiol Heart Circ Physiol
Main Authors: Cui, Xizhong, Xu, Wanying, Neupane, Pranita, Weiser-Schlesinger, Andie, Weng, Ray, Pockros, Benjamin, Li, Yan, Moayeri, Mahtab, Leppla, Stephen H., Fitz, Yvonne, Eichacker, Peter Q.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580392/
https://ncbi.nlm.nih.gov/pubmed/30767685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00685.2018
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