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Analysis of crystalline and solution states of ligand-free spermidine N-acetyltransferase (SpeG) from Escherichia coli

Spermidine N-acetyltransferase (SpeG) transfers an acetyl group from acetyl-coenzyme A to an N-terminal amino group of intracellular spermidine. This acetylation inactivates spermidine, reducing the polyamine toxicity that tends to occur under certain chemical and physical stresses. The structure of...

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Bibliografiske detaljer
Udgivet i:Acta Crystallogr D Struct Biol
Main Authors: Filippova, Ekaterina V., Weigand, Steven, Kiryukhina, Olga, Wolfe, Alan J., Anderson, Wayne F.
Format: Artigo
Sprog:Inglês
Udgivet: International Union of Crystallography 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580228/
https://ncbi.nlm.nih.gov/pubmed/31205017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798319006545
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