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A novel polyamine allosteric site of SpeG from Vibrio cholerae is revealed by its dodecameric structure

Spermidine N-acetyltransferase, encoded by the gene speG, catalyzes the initial step in the degradation of polyamines and is a critical enzyme for determining the polyamine concentrations in bacteria. In Escherichia coli, studies have shown that SpeG is the enzyme responsible for acetylating spermid...

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Vydáno v:J Mol Biol
Hlavní autoři: Filippova, Ekaterina V., Kuhn, Misty L., Osipiuk, Jerzy, Kiryukhina, Olga, Joachimiak, Andrzej, Ballicora, Miguel A., Anderson, Wayne F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355314/
https://ncbi.nlm.nih.gov/pubmed/25623305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.01.009
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