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Knockdown of lncRNA-HOTAIR downregulates the drug-resistance of breast cancer cells to doxorubicin via the PI3K/AKT/mTOR signaling pathway

The resistance to chemotherapeutic drugs is a critical feature of breast cancer recurrence and metastasis. Long non-coding RNAs (LncRNAs) serve key roles in tumor drug resistance. LncRNA-HOX transcript antisense RNA (HOTAIR) has been reported to be overexpressed in certain types of cancer and may be...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Li, Zhixiang, Qian, Jun, Li, Jing, Zhu, Chao
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580102/
https://ncbi.nlm.nih.gov/pubmed/31281438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2019.7629
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