TET1 reprograms the epithelial ovarian cancer epigenome and reveals casein kinase 2α as a therapeutic target

Ten-eleven translocation methylcytosine dioxygenase-1, TET1, takes part in active DNA demethylation. However, our understanding of DNA demethylation in cancer biology and its clinical significance remain limited. This study showed that TET1 expression correlated with poor survival in advanced-stage...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Chen, Lin-Yu, Huang, Rui-Lan, Chan, Michael W.Y., Yan, Pearlly S., Huang, Tien-Shuo, Wu, Ren-Chin, Rahmanto, Yohan Suryo, Su, Po-Hsuan, Weng, Yu-Chun, Chou, Jian-Liang, Chao, Tai-Kuang, Wang, Yu-Chi, Shih, Ie-Ming, Lai, Hung-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579655/
https://ncbi.nlm.nih.gov/pubmed/30883733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5266
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