TET1 reprograms the epithelial ovarian cancer epigenome and reveals casein kinase 2α as a therapeutic target

Ten-eleven translocation methylcytosine dioxygenase-1, TET1, takes part in active DNA demethylation. However, our understanding of DNA demethylation in cancer biology and its clinical significance remain limited. This study showed that TET1 expression correlated with poor survival in advanced-stage...

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Publicado en:J Pathol
Autores principales: Chen, Lin-Yu, Huang, Rui-Lan, Chan, Michael W.Y., Yan, Pearlly S., Huang, Tien-Shuo, Wu, Ren-Chin, Rahmanto, Yohan Suryo, Su, Po-Hsuan, Weng, Yu-Chun, Chou, Jian-Liang, Chao, Tai-Kuang, Wang, Yu-Chi, Shih, Ie-Ming, Lai, Hung-Cheng
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579655/
https://ncbi.nlm.nih.gov/pubmed/30883733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5266
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