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Lipid nanoparticles for delivery of messenger RNA to the back of the eye
Retinal gene therapy has had unprecedented success in generating treatments that can halt vision loss. However, immunogenic response and long-term toxicity with the use of viral vectors remain a concern. Non-viral vectors are relatively non-immunogenic, scalable platforms that have limited success w...
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| Pubblicato in: | J Control Release |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6579630/ https://ncbi.nlm.nih.gov/pubmed/30986436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2019.04.015 |
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