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The effects of PEGylation on LNP based mRNA delivery to the eye
Gene therapy is now an effective approach to treat many forms of retinal degeneration. Delivery agents that are cell-specific, allow for multiple dosing regimens, and have low immunogenicity are needed to expand the utility of gene therapy for the retina. We generated eight novel lipid nanoparticles...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7595320/ https://ncbi.nlm.nih.gov/pubmed/33119640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0241006 |
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