Defining new mechanistic roles for αII spectrin in cardiac function

Spectrins are cytoskeletal proteins essential for membrane biogenesis and regulation and serve critical roles in protein targeting and cellular signaling. αII spectrin (SPTAN1) is one of two α spectrin genes and αII spectrin dysfunction is linked to alterations in axon initial segment formation, cor...

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Опубликовано в: :J Biol Chem
Главные авторы: Lubbers, Ellen R., Murphy, Nathaniel P., Musa, Hassan, Huang, Claire Yu-Mei, Gupta, Rohan, Price, Morgan V., Han, Mei, Daoud, Georges, Gratz, Daniel, El Refaey, Mona, Xu, Xianyao, Hoeflinger, Nicole K., Friel, Emma L., Lancione, Peter, Wallace, Michael J., Cavus, Omer, Simmons, Samantha L., Williams, Jordan L., Skaf, Michel, Koenig, Sara N., Janssen, Paul M. L., Rasband, Matthew N., Hund, Thomas J., Mohler, Peter J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2019
Предметы:
Molecular Bases of Disease
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579463/
https://ncbi.nlm.nih.gov/pubmed/31064843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007714
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