Defining new mechanistic roles for αII spectrin in cardiac function

Spectrins are cytoskeletal proteins essential for membrane biogenesis and regulation and serve critical roles in protein targeting and cellular signaling. αII spectrin (SPTAN1) is one of two α spectrin genes and αII spectrin dysfunction is linked to alterations in axon initial segment formation, cor...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Lubbers, Ellen R., Murphy, Nathaniel P., Musa, Hassan, Huang, Claire Yu-Mei, Gupta, Rohan, Price, Morgan V., Han, Mei, Daoud, Georges, Gratz, Daniel, El Refaey, Mona, Xu, Xianyao, Hoeflinger, Nicole K., Friel, Emma L., Lancione, Peter, Wallace, Michael J., Cavus, Omer, Simmons, Samantha L., Williams, Jordan L., Skaf, Michel, Koenig, Sara N., Janssen, Paul M. L., Rasband, Matthew N., Hund, Thomas J., Mohler, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579463/
https://ncbi.nlm.nih.gov/pubmed/31064843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007714
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