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Defining new mechanistic roles for αII spectrin in cardiac function

Spectrins are cytoskeletal proteins essential for membrane biogenesis and regulation and serve critical roles in protein targeting and cellular signaling. αII spectrin (SPTAN1) is one of two α spectrin genes and αII spectrin dysfunction is linked to alterations in axon initial segment formation, cor...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Lubbers, Ellen R., Murphy, Nathaniel P., Musa, Hassan, Huang, Claire Yu-Mei, Gupta, Rohan, Price, Morgan V., Han, Mei, Daoud, Georges, Gratz, Daniel, El Refaey, Mona, Xu, Xianyao, Hoeflinger, Nicole K., Friel, Emma L., Lancione, Peter, Wallace, Michael J., Cavus, Omer, Simmons, Samantha L., Williams, Jordan L., Skaf, Michel, Koenig, Sara N., Janssen, Paul M. L., Rasband, Matthew N., Hund, Thomas J., Mohler, Peter J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579463/
https://ncbi.nlm.nih.gov/pubmed/31064843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007714
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