Defining new mechanistic roles for αII spectrin in cardiac function

Spectrins are cytoskeletal proteins essential for membrane biogenesis and regulation and serve critical roles in protein targeting and cellular signaling. αII spectrin (SPTAN1) is one of two α spectrin genes and αII spectrin dysfunction is linked to alterations in axon initial segment formation, cor...

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Udgivet i:J Biol Chem
Main Authors: Lubbers, Ellen R., Murphy, Nathaniel P., Musa, Hassan, Huang, Claire Yu-Mei, Gupta, Rohan, Price, Morgan V., Han, Mei, Daoud, Georges, Gratz, Daniel, El Refaey, Mona, Xu, Xianyao, Hoeflinger, Nicole K., Friel, Emma L., Lancione, Peter, Wallace, Michael J., Cavus, Omer, Simmons, Samantha L., Williams, Jordan L., Skaf, Michel, Koenig, Sara N., Janssen, Paul M. L., Rasband, Matthew N., Hund, Thomas J., Mohler, Peter J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2019
Fag:
Molecular Bases of Disease
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579463/
https://ncbi.nlm.nih.gov/pubmed/31064843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007714
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