Dual inhibition of glutaminase and carnitine palmitoyltransferase decreases growth and migration of glutaminase inhibition–resistant triple-negative breast cancer cells

Triple-negative breast cancers (TNBCs) lack progesterone and estrogen receptors and do not have amplified human epidermal growth factor receptor 2, the main therapeutic targets for managing breast cancer. TNBCs have an altered metabolism, including an increased Warburg effect and glutamine dependenc...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: dos Reis, Larissa Menezes, Adamoski, Douglas, Ornitz Oliveira Souza, Rodolpho, Rodrigues Ascenção, Carolline Fernanda, Sousa de Oliveira, Krishina Ratna, Corrêa-da-Silva, Felipe, Malta de Sá Patroni, Fábio, Meira Dias, Marília, Consonni, Sílvio Roberto, Mendes de Moraes-Vieira, Pedro Manoel, Silber, Ariel Mariano, Dias, Sandra Martha Gomes
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2019
Konular:
Cell Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579458/
https://ncbi.nlm.nih.gov/pubmed/31040181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008180
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