Heartland virus antagonizes type I and III interferon antiviral signaling by inhibiting phosphorylation and nuclear translocation of STAT2 and STAT1

Heartland virus (HRTV) is a pathogenic phlebovirus recently identified in the United States and related to severe fever with thrombocytopenia syndrome virus (SFTSV) emerging in Asia. We previously reported that SFTSV disrupts host antiviral responses directed by interferons (IFNs) and their downstre...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Feng, Kuan, Deng, Fei, Hu, Zhihong, Wang, Hualin, Ning, Yun-Jia
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2019
Ämnen:
Immunology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579454/
https://ncbi.nlm.nih.gov/pubmed/31040183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006563
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