Interferon-γ-Directed Inhibition of a Novel High-Pathogenic Phlebovirus and Viral Antagonism of the Antiviral Signaling by Targeting STAT1

Severe fever with thrombocytopenia syndrome (SFTS) is a life-threatening infectious disease caused by a novel phlebovirus, SFTS virus (SFTSV). Currently, there is no vaccine or antiviral available and the viral pathogenesis remains largely unknown. In this study, we demonstrated that SFTSV infection...

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Detalles Bibliográficos
Publicado en:Front Immunol
Autores principales: Ning, Yun-Jia, Mo, Qiong, Feng, Kuan, Min, Yuan-Qin, Li, Mingyue, Hou, Dianhai, Peng, Cheng, Zheng, Xin, Deng, Fei, Hu, Zhihong, Wang, Hualin
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546826/
https://ncbi.nlm.nih.gov/pubmed/31191546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01182
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