Major Histocompatibility Class II Molecules in the CNS: Increased Microglial Expression at the Onset of Narcolepsy in a Canine Model

Human narcolepsy is a neurological disorder known to be closely associated with HLA-DR2 and DQB1*0602. Because most autoimmune diseases are HLA-associated, a similar mechanism has been proposed for narcolepsy. However, neither systemic nor CNS evidence of an autoimmune abnormality has ever been repo...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Tafti, Mehdi, Nishino, Seiji, Aldrich, Michael S., Liao, Wennie, Dement, William C., Mignot, Emmanuel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 1996
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579009/
https://ncbi.nlm.nih.gov/pubmed/8764647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-15-04588.1996
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