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Potentiation of neuronal NMDA response induced by dehydroepiandrosterone and its suppression by progesterone: effects mediated via sigma receptors

We have shown previously that low doses of selective sigma (sigma)- receptor ligands potentiate the excitatory response of pyramidal neurons to NMDA in the CA3 region of the dorsal hippocampus in the rat. Because progesterone competitively displaces the binding of the ligand N-[3H]allyl-normetazocin...

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Pubblicato in:J Neurosci
Autori principali: Bergeron, R, de Montigny, C, Debonnel, G
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 1996
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6578822/
https://ncbi.nlm.nih.gov/pubmed/8558248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-03-01193.1996
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