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The sigma-1 receptor modulates NMDA receptor synaptic transmission and plasticity via SK channels in rat hippocampus

The sigma receptor (σR), once considered a subtype of the opioid receptor, is now described as a distinct pharmacological entity. Modulation of N-methyl-d-aspartate receptor (NMDAR) functions by σR-1 ligands is well documented; however, its mechanism is not fully understood. Using patch-clamp whole-...

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Detalhes bibliográficos
Main Authors: Martina, Marzia, Turcotte, Marie-Eve B, Halman, Samantha, Bergeron, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075134/
https://ncbi.nlm.nih.gov/pubmed/17068104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.116178
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