Convergent Metabotropic Signaling Pathways Inhibit SK Channels to Promote Synaptic Plasticity in the Hippocampus

Hebbian synaptic plasticity at hippocampal Schaffer collateral synapses is tightly regulated by postsynaptic small conductance (SK) channels that restrict NMDA receptor activity. SK channels are themselves modulated by G-protein-coupled signaling pathways, but it is not clear under what conditions t...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Tigaret, Cezar M., Chamberlain, Sophie E.L., Sadowski, Joseph H.L.P., Hall, Jeremy, Ashby, Michael C., Mellor, Jack R.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199408/
https://ncbi.nlm.nih.gov/pubmed/30242046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1160-18.2018
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