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Convergent Metabotropic Signaling Pathways Inhibit SK Channels to Promote Synaptic Plasticity in the Hippocampus

Hebbian synaptic plasticity at hippocampal Schaffer collateral synapses is tightly regulated by postsynaptic small conductance (SK) channels that restrict NMDA receptor activity. SK channels are themselves modulated by G-protein-coupled signaling pathways, but it is not clear under what conditions t...

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Vydáno v:J Neurosci
Hlavní autoři: Tigaret, Cezar M., Chamberlain, Sophie E.L., Sadowski, Joseph H.L.P., Hall, Jeremy, Ashby, Michael C., Mellor, Jack R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199408/
https://ncbi.nlm.nih.gov/pubmed/30242046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1160-18.2018
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