Downregulation of Cu/Zn superoxide dismutase leads to cell death via the nitric oxide-peroxynitrite pathway

We previously showed that the downregulation of Cu/Zn superoxide dismutase (SOD1) activity in PC12 cells by exposure to an appropriate antisense oligonucleotide causes their apoptotic death. In this report, we used this model to examine the pathways by which SOD1 downregulation leads to death and to...

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Detaylı Bibliyografya
Yayımlandı:J Neurosci
Asıl Yazarlar: Troy, CM, Derossi, D, Prochiantz, A, Greene, LA, Shelanski, ML
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 1996
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6578729/
https://ncbi.nlm.nih.gov/pubmed/8613791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-01-00253.1996
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