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Downregulation of Cu/Zn superoxide dismutase leads to cell death via the nitric oxide-peroxynitrite pathway
We previously showed that the downregulation of Cu/Zn superoxide dismutase (SOD1) activity in PC12 cells by exposure to an appropriate antisense oligonucleotide causes their apoptotic death. In this report, we used this model to examine the pathways by which SOD1 downregulation leads to death and to...
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| Published in: | J Neurosci |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Society for Neuroscience
1996
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6578729/ https://ncbi.nlm.nih.gov/pubmed/8613791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-01-00253.1996 |
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