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Opioid desensitization: interactions with G-protein-coupled receptors in the locus coeruleus
In rat locus coeruleus (LC) neurons, alpha 2 adrenoceptors, mu-opioid and somatostatin receptors all activate the same potassium conductance. Chronic treatment with morphine causes a loss of sensitivity that is specific to the mu-opioid response, with no change in the alpha 2 adrenoceptor-mediated r...
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| Udgivet i: | J Neurosci |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Society for Neuroscience
1996
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6578565/ https://ncbi.nlm.nih.gov/pubmed/8778299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-04-01479.1996 |
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