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Opioid desensitization: interactions with G-protein-coupled receptors in the locus coeruleus

In rat locus coeruleus (LC) neurons, alpha 2 adrenoceptors, mu-opioid and somatostatin receptors all activate the same potassium conductance. Chronic treatment with morphine causes a loss of sensitivity that is specific to the mu-opioid response, with no change in the alpha 2 adrenoceptor-mediated r...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Fiorillo, CD, Williams, JT
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 1996
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6578565/
https://ncbi.nlm.nih.gov/pubmed/8778299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-04-01479.1996
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