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Somatic gene transfer of NGF to the aged brain: behavioral and morphological amelioration

Primary fibroblasts modified to secrete nerve growth factor (NGF) were implanted into the nucleus basalis magnocellularis (NBM) of aged memory impaired rats. The NGF-producing fibroblasts survived for 6 weeks following transplantation and continued expressing NGF mRNA through the duration of the exp...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Chen, KS, Gage, FH
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6577764/
https://ncbi.nlm.nih.gov/pubmed/7722631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.15-04-02819.1995
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