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Somatic gene transfer of nerve growth factor promotes the survival of axotomized septal neurons and the regeneration of their axons in adult rats

Intracerebral grafts consisting of primary fibroblasts genetically engineered to express NGF were used to assess the regenerative capacity of cholinergic neurons of the adult rat septum. Our data reveal that NGF-producing grafts sustain a significantly higher proportion of NGF receptor-immunoreactiv...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Kawaja, MD, Rosenberg, MB, Yoshida, K, Gage, FH
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575835/
https://ncbi.nlm.nih.gov/pubmed/1319481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.12-07-02849.1992
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