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Somatic gene transfer of nerve growth factor promotes the survival of axotomized septal neurons and the regeneration of their axons in adult rats
Intracerebral grafts consisting of primary fibroblasts genetically engineered to express NGF were used to assess the regenerative capacity of cholinergic neurons of the adult rat septum. Our data reveal that NGF-producing grafts sustain a significantly higher proportion of NGF receptor-immunoreactiv...
Gespeichert in:
| Veröffentlicht in: | J Neurosci |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Neuroscience
1992
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6575835/ https://ncbi.nlm.nih.gov/pubmed/1319481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.12-07-02849.1992 |
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