Nutrient‐sensitive transcription factors TFEB and TFE3 couple autophagy and metabolism to the peripheral clock

Autophagy and energy metabolism are known to follow a circadian pattern. However, it is unclear whether autophagy and the circadian clock are coordinated by common control mechanisms. Here, we show that the oscillation of autophagy genes is dependent on the nutrient‐sensitive activation of TFEB and...

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Vydáno v:EMBO J
Hlavní autoři: Pastore, Nunzia, Vainshtein, Anna, Herz, Niculin J, Huynh, Tuong, Brunetti, Lorenzo, Klisch, Tiemo J, Mutarelli, Margherita, Annunziata, Patrizia, Kinouchi, Kenichiro, Brunetti‐Pierri, Nicola, Sassone‐Corsi, Paolo, Ballabio, Andrea
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6576167/
https://ncbi.nlm.nih.gov/pubmed/31126958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018101347
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