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Nutrient‐sensitive transcription factors TFEB and TFE3 couple autophagy and metabolism to the peripheral clock

Autophagy and energy metabolism are known to follow a circadian pattern. However, it is unclear whether autophagy and the circadian clock are coordinated by common control mechanisms. Here, we show that the oscillation of autophagy genes is dependent on the nutrient‐sensitive activation of TFEB and...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Pastore, Nunzia, Vainshtein, Anna, Herz, Niculin J, Huynh, Tuong, Brunetti, Lorenzo, Klisch, Tiemo J, Mutarelli, Margherita, Annunziata, Patrizia, Kinouchi, Kenichiro, Brunetti‐Pierri, Nicola, Sassone‐Corsi, Paolo, Ballabio, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6576167/
https://ncbi.nlm.nih.gov/pubmed/31126958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018101347
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