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The neurotoxic carboxy-terminal fragment of the Alzheimer amyloid precursor binds specifically to a neuronal cell surface molecule: pH dependence of the neurotoxicity and the binding

One of the hallmarks of Alzheimer's disease neurodegeneration is the accumulation of deposits of amyloid in neuritic plaques and in the cerebral vasculature. Recent studies have implicated carboxy-terminal fragments of the Alzheimer amyloid precursor protein (beta APP) in the processes of amylo...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Kozlowski, MR, Spanoyannis, A, Manly, SP, Fidel, SA, Neve, RL
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 1992
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575880/
https://ncbi.nlm.nih.gov/pubmed/1578262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.12-05-01679.1992
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