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Pathophysiological Roles of Amyloidogenic Carboxy-Terminal Fragments of the β-Amyloid Precursor Protein in Alzheimer’s Disease
Several lines of evidence suggest that some of the neurotoxicity in Alzheimer’s disease (AD) is attributed to proteolytic fragments of amyloid precursor protein (APP) and β-amyloid (Aβ) may not be the sole active component involved in the pathogenesis of AD. The potential effects of other cleavage p...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier
2005-01-01
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Colecção: | Journal of Pharmacological Sciences |
Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S1347861319322285 |
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