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Pathophysiological Roles of Amyloidogenic Carboxy-Terminal Fragments of the β-Amyloid Precursor Protein in Alzheimer’s Disease

Several lines of evidence suggest that some of the neurotoxicity in Alzheimer’s disease (AD) is attributed to proteolytic fragments of amyloid precursor protein (APP) and β-amyloid (Aβ) may not be the sole active component involved in the pathogenesis of AD. The potential effects of other cleavage p...

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Detalhes bibliográficos
Main Authors: Keun-A Chang, Yoo-Hun Suh
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2005-01-01
Colecção:Journal of Pharmacological Sciences
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S1347861319322285
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