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4-aminopyridine-induced epileptiform activity and a GABA-mediated long- lasting depolarization in the rat hippocampus

Two types of spontaneous filed potentials were recorded in rat hippocampal slices after addition of 4-aminopyridine (4-AP; 50 microM). One consisted of brief, epileptiform discharges that occurred at 0.6 +/- 0.2 sec-1 in the CA3 and CA1 areas. The other type occurred less frequently (0.036 +/- 0.013...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Perreault, P, Avoli, M
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 1992
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575697/
https://ncbi.nlm.nih.gov/pubmed/1309571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.12-01-00104.1992
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