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Temporal lobe epileptiform activity following systemic administration of 4-aminopyridine in rats
PURPOSE: The K(+) channel blocker 4-aminopyridine (4AP) induces epileptiform synchronization in brain slices maintained in vitro without interfering with γ-aminobutyric acid (GABA)(A) receptor–mediated inhibition and, actually, even enhancing it. The hypothesis that similar electrographic epileptifo...
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| Publicado en: | Epilepsia |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4878895/ https://ncbi.nlm.nih.gov/pubmed/23521339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.12041 |
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