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The anti-ictogenic effects of levetiracetam are mirrored by interictal spiking and high-frequency oscillation changes in a model of temporal lobe epilepsy

PURPOSE: Mesial temporal lobe epilepsy (MTLE) is the most prevalent type of partial epileptic disorders. In this study, we have analyzed the impact of levetiracetam (LEV) in the pilocarpine model of MTLE. METHODS: Sprague-Dawley rats (n = 19) were injected with pilocarpine (380 mg/kg, i.p.) to induc...

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發表在:Seizure
Main Authors: Lévesque, Maxime, Behr, Charles, Avoli, Massimo
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880465/
https://ncbi.nlm.nih.gov/pubmed/25645630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.seizure.2014.11.008
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