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The anti-ictogenic effects of levetiracetam are mirrored by interictal spiking and high-frequency oscillation changes in a model of temporal lobe epilepsy

PURPOSE: Mesial temporal lobe epilepsy (MTLE) is the most prevalent type of partial epileptic disorders. In this study, we have analyzed the impact of levetiracetam (LEV) in the pilocarpine model of MTLE. METHODS: Sprague-Dawley rats (n = 19) were injected with pilocarpine (380 mg/kg, i.p.) to induc...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Seizure
Päätekijät: Lévesque, Maxime, Behr, Charles, Avoli, Massimo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880465/
https://ncbi.nlm.nih.gov/pubmed/25645630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.seizure.2014.11.008
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