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The anti-ictogenic effects of levetiracetam are mirrored by interictal spiking and high-frequency oscillation changes in a model of temporal lobe epilepsy

PURPOSE: Mesial temporal lobe epilepsy (MTLE) is the most prevalent type of partial epileptic disorders. In this study, we have analyzed the impact of levetiracetam (LEV) in the pilocarpine model of MTLE. METHODS: Sprague-Dawley rats (n = 19) were injected with pilocarpine (380 mg/kg, i.p.) to induc...

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Detaylı Bibliyografya
Yayımlandı:Seizure
Asıl Yazarlar: Lévesque, Maxime, Behr, Charles, Avoli, Massimo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880465/
https://ncbi.nlm.nih.gov/pubmed/25645630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.seizure.2014.11.008
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