Role of KCC2-Dependent Potassium Efflux in 4-Aminopyridine-Induced Epileptiform Synchronization

A balance between excitation and inhibition is necessary to maintain stable brain network dynamics. Traditionally, seizure activity is believed to arise from the breakdown of this delicate balance in favor of excitation with loss of inhibition. Surprisingly, recent experimental evidence suggests tha...

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Bibliographic Details
Published in:Neurobiol Dis
Main Authors: González, Oscar C, Shiri, Zahra, Krishnan, Giri P, Myers, Timothy L, Williams, Sylvain, Avoli, Massimo, Bazhenov, Maxim
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5710807/
https://ncbi.nlm.nih.gov/pubmed/29045814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2017.10.011
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