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Kappa- and delta-opioids block sympathetically dependent hyperalgesia

Direct hyperalgesia induced by prostaglandin E2 (PGE2) can be blocked by mu- but not delta- or kappa-opioids. However, there is evidence that kappa- and delta-opioid receptors are located on sympathetic postganglionic neuron (SPGN) terminals, which mediate bradykinin (BK) hyperalgesia via SPGN-termi...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Taiwo, YO, Levine, JD
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575370/
https://ncbi.nlm.nih.gov/pubmed/2010815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.11-04-00928.1991
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