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Hyperalgesia during acute opioid abstinence: evidence for a nociceptive facilitating function of the rostral ventromedial medulla

Naloxone-precipitated opioid abstinence is associated with enhancement of reflex responses to noxious stimulation (hyperalgesia). The present experiments in lightly anesthetized rats were designed to determine (1) whether neurons in the rostral ventromedial medulla (RVM) contribute to this enhanceme...

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Publicado en:J Neurosci
Autores principales: Kaplan, H, Fields, HL
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 1991
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575327/
https://ncbi.nlm.nih.gov/pubmed/2027054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.11-05-01433.1991
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