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Cellular Basis for Opioid Potentiation in the Rostral Ventromedial Medulla of Rats with Persistent Inflammatory Nociception

Direct inhibition of pain facilitatory neurons in the rostral ventromedial medulla (RVM) is one mechanism by which mu opioid receptor (MOPr) agonists are proposed to produce antinociception. The antinociceptive and anti-hyperalgesic effects of the MOPr agonist DAMGO are enhanced after intraplantar i...

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Détails bibliographiques
Auteurs principaux: Zhang, Liang, Hammond, Donna L.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860801/
https://ncbi.nlm.nih.gov/pubmed/20172653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2010.01.017
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