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Processing of beta-amyloid precursor protein in microglia and astrocytes favors an internal localization over constitutive secretion
Microglial cells and astrocytes are closely associated with nearly all compact deposits of the amyloid beta-protein found in the senile plaques characteristic of Alzheimer's disease and trisomy 21. The biosynthesis and metabolic fate of the beta-amyloid precursor protein (beta APP) in astrocyte...
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| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6575298/ https://ncbi.nlm.nih.gov/pubmed/1744690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.11-12-03783.1991 |
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