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Predicting Site-Binding Modes of Ions and Water to Nucleic Acids Using Molecular Solvation Theory

Site binding of ions and water shapes nucleic acids folding, dynamics, and biological function, complementing the more diffuse, nonspecific “territorial” ion binding. Unlike territorial binding, prediction of site-specific binding to nucleic acids remains an unsolved challenge in computational bioph...

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Détails bibliographiques
Publié dans:J Am Chem Soc
Auteurs principaux: Giambasu, George M., Case, David A., York, Darrin M.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6574206/
https://ncbi.nlm.nih.gov/pubmed/30632365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b11474
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