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Predicting Site-Binding Modes of Ions and Water to Nucleic Acids Using Molecular Solvation Theory

Site binding of ions and water shapes nucleic acids folding, dynamics, and biological function, complementing the more diffuse, nonspecific “territorial” ion binding. Unlike territorial binding, prediction of site-specific binding to nucleic acids remains an unsolved challenge in computational bioph...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Giambasu, George M., Case, David A., York, Darrin M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6574206/
https://ncbi.nlm.nih.gov/pubmed/30632365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b11474
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