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Mutation Causing Autosomal Dominant Nocturnal Frontal Lobe Epilepsy Alters Ca(2+) Permeability, Conductance, and Gating of Human α4β2 Nicotinic Acetylcholine Receptors
A mutation (S247F) in the channel-lining domain (M2) of the α4 nicotinic acetylcholine receptor (AChR) subunit has previously been linked genetically to autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE). To better understand the functional significance of this mutation, we characterized th...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Neurosci |
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| Κύριοι συγγραφείς: | , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Society for Neuroscience
1997
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6573611/ https://ncbi.nlm.nih.gov/pubmed/9364050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-23-09035.1997 |
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