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Upregulation of the Endosomal-Lysosomal Pathway in the Trembler-J Neuropathy

A nonconservative leucine to proline mutation in peripheral myelin protein 22 (PMP22) causes the Trembler-J (Tr(J)) neuropathy in mice and humans. The expression levels and localization of the PMP22 protein in the Tr(J) mouse have not been previously determined. The aim of our studies was to reevalu...

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Publicat a:J Neurosci
Autors principals: Notterpek, Lucia, Shooter, Eric M., Snipes, G. Jackson
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573524/
https://ncbi.nlm.nih.gov/pubmed/9151736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-11-04190.1997
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