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Massive Loss of Mid- and Hindbrain Neurons during Embryonic Development of Homozygous Lurcher Mice
The mouse neurological mutant lurcher (Lc) results from a semidominant mutation. Heterozygous Lc/+ mice are viable but ataxic because Lc/+ Purkinje cells die by apoptosis within the first 3 weeks of life. Lc/Lcmice die shortly after birth. To aid in understanding the function of the lurcher gene pro...
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| Published in: | J Neurosci |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Society for Neuroscience
1997
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6573489/ https://ncbi.nlm.nih.gov/pubmed/9065501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-07-02400.1997 |
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