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Mechanistic basis of L-lactate transport in the SLC16 solute carrier family

In human and other mammalian cells, transport of L-lactate across plasma membranes is mainly catalyzed by monocarboxylate transporters (MCTs) of the SLC16 solute carrier family. MCTs play an important role in cancer metabolism and are promising targets for tumor treatment. Here, we report the crysta...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Bosshart, Patrick D., Kalbermatter, David, Bonetti, Sara, Fotiadis, Dimitrios
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573034/
https://ncbi.nlm.nih.gov/pubmed/31201333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10566-6
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